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Palliser Capital doubled down on its call for a review of Rio Tinto’s dual listing in London and Sydney, adding that it now has the backing of more than 100 shareholders.

Lamb Weston Holdings said it was replacing its chief executive and slashing guidance again as demand for frozen potato products sputters, sending shares sharply lower.

An experimental Parkinson’s drug missed its primary goal in a mid-stage trial, Roche said, in what is the second setback this week for candidate treatments for the neurodegenerative condition.

Dollar Tree said it has named Michael Creedon Jr. as the discount retailer’s permanent chief executive, removing the interim tag he has carried since early November.

The action comes over contract negotiations and the company’s refusal to recognize the Teamsters labor union.